Glomerulonephritis is a progressive kidney disease that involves the glomeruli, the individual filtering units of the kidney that produce urine. When the glomeruli become inflamed, the kidneys can't filter urine properly. This results in a buildup of excess fluid and toxins in the body. Glomerulonephritis can lead to chronic renal (kidney) failure.
There are two main types of glomerulonephritis: primary and secondary. Primary glomerulonephritis affects the kidneys directly, while in secondary glomerulonephritis the kidneys are damaged as a result of another illness. Glomerulonephritis seems to happen twice as often in males as in females.