Non-Alcoholic Fatty Liver Disease

Several risk factors increase the likelihood of a person developing NAFLD. These risk factors include:

• diabetes
• excess weight and obesity
• high levels of fat in the blood (also known as hyperlipidemia)

It appears that people with metabolic syndrome are more likely to develop some form of NAFLD. Metabolic syndrome is a condition that can include high blood pressure, high cholesterol or blood fat levels, obesity, or an inability to regulate sugar (insulin resistance).

However, people without metabolic syndrome or any of its risk factors can also develop NAFLD. Taking certain medications such as corticosteroids, antiretrovirals, and immune-suppressing medications may also increase the chance of developing NAFLD.

NAFLD is usually not associated with any symptoms and is discovered with routine blood tests.

If the mild form of the condition develops into NASH or cirrhosis, a person may notice other symptoms including loss of appetite, discomfort in the upper right abdomen, weight loss, jaundice (yellow skin or eyes), dark urine, swollen legs, swollen feet, easy bruising, and mental problems (e.g., memory loss).

Several different tests may be needed to identify NAFLD, including blood tests, ultrasound, biopsy, CT scan, or MRI scan:

• blood tests: Liver inflammation or damage leads to increased liver enzyme levels that can be detected with a simple blood test.
• ultrasound: Using a sound probe, a technician takes pictures of the liver. A doctor uses this image to look for any damage to the liver or increased size, which may indicate swelling or inflammation.
• biopsy: Used alone or in combination with one of the other tests, a biopsy is the best way to confirm NAFLD but it is not used routinely. This technique requires making an incision in order to reach the liver and remove a small sample of liver tissue. Analysis of the tissue shows whether or not the cells are normal.
• CT scan: This type of scan uses X-rays to see the liver. The image is a cross-section of the liver.
• MRI: This type of scan uses radio waves to produce a 3D image of the liver.

Your doctor may also ask you questions relating to your medical history, diet, and alcohol consumption. Ruling out conditions such as hepatitis B and C (which also damage the liver) is important before making the diagnosis of NAFLD.

Since NALFD is associated with other risk factors such as obesity, diabetes, and high cholesterol levels, getting some or all of these conditions under control can help manage the disease.

Treatment for a person with NAFLD may include:

• regular physical activity
• reducing toxic substances in your diet (e.g., alcohol)
• taking other certain medications that are less likely to cause NAFLD
• controlling high cholesterol
• controlling diabetes

Preventing this condition requires looking after your health every day. Reaching and maintaining a healthy weight by making healthy food choices and exercising regularly are important. Keeping conditions such as diabetes and high cholesterol in control may also reduce your risk of NAFLD.

For information about nutrition and exercise, refer to these publications:

• Canada's Food Guide
• Canada's Physical Activity Guide to Healthy Active Living

All material copyright MediResource Inc. 1996 – 2018. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/condition/getcondition/Non-Alcoholic-Fatty-Liver-Disease